James L. Oschman, Ph.D.
N.O.R.A.
PMB 170
827 Central Avenue
Dover, NH 03820
October 7, 2004 Report on the mechanism of action of the EB-PRO with regard to physiological detoxification. molecule diagram As shown here there are 3 ways toxic materials (ions,
molecules, clusters of molecules) can become trapped in the matrix. By matrix, I am referring to the extracellular, cytoplasmic, and nuclear matrices that form a continuously
interconnected fabric extending throughout the body. It is the operation of this system that is compromised by toxic accumulation. The functioning of virtually all of the physiological
systems will be enhanced by toxic removal.

In the illustration, (a) refers to mechanical trapping; (b) refers to ionic binding to charges on the matrix surfaces; and (c) refers to hydrophobic & hydrophilic binding (e.g. uncharged
molecules adhering to the matrix).

You will note that I have used a positive charge, such as a cation, for example (b). I have done this because the matrix (the hyaluronan gel) is predominantly negatively charged. The
illustration on the top of the next page shows the structure of the gel and its charges. The hyaluronan has a number of remarkable and important properties:

* Regulates cell division and movement
* Huge domain
* Molecular weight 3-4 million
* Randomly coiled
* Stiff due to H bonds
* A large hydrated sphere w/ a radius of 200nm
* Abundant fixed strongly negative charges

The matrix contains other charged molecules, such as other acidic glycosaminoglycans and collagen that are also capable of trapping toxins. I have referred to the hyaluronan gel
because it is the dominant component of the matrix and its ion exchange properties are well established. For a review of this topic, see Comper WD, Laurent 1978. Note also that there
are some positive charges on the gel, and it will therefore have some capacity to bind anions.

foot diagram Given the physicochemical properties of the gel, there are several ways of releasing toxins bound to the matrix. Changes in charge density and changes in geometry will
release both ions or other charged species and toxic compounds trapped in the matrix. There are good reasons that the situation set up by using the EB-PRO should change both local
and global charge density on the matrix as well as change its geometry. The changes in charge density will, in turn, affect physiological pH, because the charge network binds hydrogen
ions.

The science behind the effects of the EB-PRO on detoxification involves research on the properties of the acupuncture meridians and skin, and the ion exchange and water-binding
properties of the gel. There are many meridian points on the feet, representing the distal terminals of meridian systems. Hence immersing the feet in the foot bath will enable electrical
contact with all of the primary meridians in the body. Adding salt to the water in the foot bath is essential to make the fluid conductive.

The meridians reside in the matrix, and have branches that reach into every nook and cranny of the body, even into individual cells as shown in the diagram below. The relationship
between meridians and connective tissue has been known for thousands of years and has recently been confirmed by a study published in a peer reviewed scientific journal.

matrix diagram A number of studies have shown that the meridians are electrically conductive. Hence the electrical polarities set up by the EB-PRO should be conducted throughout the
matrix and thereby change the charge density on a global or systemic scale (by �global� or �systemic� I mean throughout the entire body).

The ways changes in charge density bring about toxin release are well established. Again, the research of Laurent and colleagues in Sweden is key. The geometry of the gel and its
water and ion binding characteristics are dependent on the mutual attraction and repulsion of the charges on the gel matrix. Change charge density, and you will change the geometry,
releasing trapped molecules. Changing the local charge configuration will release material that is ionically bound. The final link in the process is to describe how toxins released by the
above process can find their way into the footbath. Again, research on the meridians has shown that they are capable of acting as channels for the transport or diffusion of various
molecules. Radiographic studies using scintiphotography showed that a radioactive dye, technetium-99, injected into a meridian, flow linearly along the meridian pathway and well up
into small circles at the classical acupuncture. The electrical polarities set up by the EB-PRO should cause toxin molecules to migrate along the meridians to the bottoms of the feet by a
process akin to electrophoresis. This process is defined as the migration of charged colloidal particles or molecules through a solution under the influence of an applied electric field.

foot diagram The meridians are one of several pathways for toxins released from the matrix to exit the body. Capillaries and lymphatic channels will also pick up toxins and carry them to
the liver and kidneys, where they will be detoxified and/or excreted. There are also spaces within the skin that can support the flow of materials released from the matrix. For example,
the innermost layer of the skin, the corium [dermis] is relatively rich in intercellular spaces through which ions and other solutes may pass freely. Its ready permeability to ions has been
observed by Papa and Kligman who found that the cationic dye, methylene blue, when driven into the sweat gland by strong electrical currents, migrates down the duct to the level of
the dermis where it passes laterally (horizontally).

Results:
Comper WD, Laurent TC, 1978. Physiological function of connective tissue polysaccharides. Physiol Rev. Jan;58(1):255-315.

Matsumoto K Birch S 1988. Hara diagnosis: Reflections on the sea. Redwing Book Company, Brookline, MA, 484 pages.

Langevin HM, Yandow, JA 2002. Relationship of acupuncture points and meridians to connective tissue planes. The Anatomical Record 269:257-265.

Becker, R., M. Reichmanis and A. Marino. Electrophysiological correlates of acupuncture points and meridians. Psychoenergetic Systems 1: 105, 1976; Motoyama, H.
Electrophysiological and preliminary biochemical studies of skin properties in relation to the acupuncture meridian. International Association for Religion and Parapsychology 6: 1-36,
1980; Reichmannis, M., A.A. Marion and R.O. Becker. D.C. skin conductance variation at acupuncture loci. American Journal of Chinese Medicine 4: 69-72, 1976; Reihsner, R., B.
Balogh and E.J. Menzel. Two-dimensional elastic properties of human skin in terms of an incremental model at the in vivo configuration. Med. Eng. Phy. 17: 304-313, 1995; Tiller, W.A,
What do electrodermal diagnostic acupuncture instruments really measure. American Journal of Acupuncture 15(1), 18-23, 1987.

Darras JC, de Vernejoul P, Albarede P, et al. Nuclear medicine investigation of transmission of acupuncture information. Acupuncture Med. 1993; 11:22-28.

C. M. Papa and A. M. Kligman, J. Invest. Dermatol., P9, 139 (1962).

The contents of this brochure are for informational purposes only. Erchonia� makes no claims as to any medical benefit of the EB-Pro� and EB-305� units.
Ionic Detoxification
Ionic Detoxification with the Erchonia EB Pro Footbath-
Detoxification is a buzzword that is catching on fast. Some kinds are shams, some are dangerous if not done properly, and others can really improve your energy
levels and overall health. The EB-Pro™ is the world's most advanced ION therapy system available to date,  facilitating the body's natural processes; such as
homostatis, detoxification, and improved cellular function, all through exposure to positive and negative ions.  Learn how this device can benefit you by visiting the
following website.    

http://www.ebfootbath.com/

On a personal note, I was very skeptical about this technology when I first heard about it in 2003. However, when I had it done on me in 2004, I got some very
interesting results. First of all, I slept better than I had in years that same night I had the detox done. Second, I felt an improvement in my ability to concentrate, felt an
increase in my flexibility, and a reduction in my snoring.

I was still unsure about using it in my practice until Dr Jeff Spencer shared the fact that the EB Pro was something that he used on the pro athletes he treated. He
stated that it greatly sped their recovery from injuries because it had the ability to quickly reduce the inflammation that usually occurs after an injury is sustained.
Additionally, it helps flush out the "cellular debris" that gathers at the site of the injury as the body tries to heal itself.

There is ample anecdotal evidence to support the use of the EB Pro to improve health. However, the most powerful thing is to experience it firsthand and see if it
actually works for YOU. That's why I am offering you the FREE FIRST SESSION described above. Simply call our office at 626-338-3600, and let us know that you
want to get the Online Detox Special. Again, there are no obligations for further sessions and no hidden charges.
If you want to read more about the detox unit and the research behind it, follow the link above or read the description below.
ONLINE SPECIAL!

FREE FIRST SESSION!

NO OBLIGATION FOR FURTHER TREATMENT.
TRY IT OUT AND FEEL FIRSTHAND THE EFFECTS OF DETOXIFICATION
Click on the pictures above to hear James Oschman, PhD, explain how the Ionic Detox works. Part 1 is in the left picture,  part 2 is in the right